SYNTHESIS OF NEW GLYCEROLIPIDS LINKED TO HYDROXAMATE DERIVATIVES DESIGNED FOR 2-DIMENSIONAL CRYSTALLIZATION OF AMINOPEPTIDASE-M

The synthesis of glycerolipids linked to hydroxamate derivatives designed for two-dimensional crystallization of aminopeptidase M is reported. The lipid moieties are readily obtained using a convergent pathway. Their structure allows the introduction of a wide variety of ligands of biological intere...

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Bibliographic Details
Published inHelvetica chimica acta Vol. 75; no. 8; pp. 2538 - 2544
Main Authors ALTENBURGER, JM, LEBEAU, L, MIOSKOWSKI, C, SCHIRLIN, D
Format Journal Article
LanguageEnglish
Published MALDEN Wiley 01.01.1992
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
PHOSPHOLIPIDS
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Summary:The synthesis of glycerolipids linked to hydroxamate derivatives designed for two-dimensional crystallization of aminopeptidase M is reported. The lipid moieties are readily obtained using a convergent pathway. Their structure allows the introduction of a wide variety of ligands of biological interest.
ISSN:0018-019X
DOI:10.1002/hlca.19920750808