MICROWAVE-INDUCED ORGANIC-REACTION ENHANCEMENT CHEMISTRY .4. CONVENIENT SYNTHESIS OF ENANTIOPURE ALPHA-HYDROXY-BETA-LACTAMS

• Published in: Tetrahedron letters Vol. 33; no. 25; pp. 3603 - 3606
• Main Authors: BANIK, BK, MANHAS, MS, KALUZA, Z, BARAKAT, KJ, BOSE, AK
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier 16.06.1992
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; ENANTIOSPECIFIC SYNTHESIS; MICROWAVE-INDUCED ORGANIC REACTIONS; ALPHA-HYDROXY-BETA-LACTAMS; L-(S)-GLYCERALDEHYDE ACETONIDE

A convenient and rapid synthesis of enantiopure alpha-hydroxy-beta-lactams using microwave-induced organic reaction enhancement chemistry has been developed. Reactions in domestic microwave ovens, which are very convenient and economical for small scale work in research or leaching laboratories, can...