MICROWAVE-INDUCED ORGANIC-REACTION ENHANCEMENT CHEMISTRY .4. CONVENIENT SYNTHESIS OF ENANTIOPURE ALPHA-HYDROXY-BETA-LACTAMS

A convenient and rapid synthesis of enantiopure alpha-hydroxy-beta-lactams using microwave-induced organic reaction enhancement chemistry has been developed. Reactions in domestic microwave ovens, which are very convenient and economical for small scale work in research or leaching laboratories, can...

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Bibliographic Details
Published inTetrahedron letters Vol. 33; no. 25; pp. 3603 - 3606
Main Authors BANIK, BK, MANHAS, MS, KALUZA, Z, BARAKAT, KJ, BOSE, AK
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 16.06.1992
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
ENANTIOSPECIFIC SYNTHESIS
MICROWAVE-INDUCED ORGANIC REACTIONS
ALPHA-HYDROXY-BETA-LACTAMS
L-(S)-GLYCERALDEHYDE ACETONIDE
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Summary:A convenient and rapid synthesis of enantiopure alpha-hydroxy-beta-lactams using microwave-induced organic reaction enhancement chemistry has been developed. Reactions in domestic microwave ovens, which are very convenient and economical for small scale work in research or leaching laboratories, can also be conducted on a preparative scale of 100-500g in simple beakers or flasks.
ISSN:0040-4039
DOI:10.1016/S0040-4039(00)92513-9