STUDIES ON LACTAMS .84. BETA-LACTAMS VIA ALPHA,BETA-UNSATURATED ACID-CHLORIDES - INTERMEDIATES FOR CARBAPENEM ANTIBIOTICS

Stereocontrolled synthesis of .alpha.-vinyl .beta.-lactams and their transformation to convenient intermediates for PS-5, PS-6, asparenomycin, and thienamycin are described.

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Bibliographic Details
Published inJournal of organic chemistry Vol. 55; no. 2; pp. 575 - 580
Main Authors MANHAS, MS, GHOSH, M, BOSE, AK
Format Journal Article
LanguageEnglish
Published WASHINGTON Amer Chemical Soc 19.01.1990
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:Stereocontrolled synthesis of .alpha.-vinyl .beta.-lactams and their transformation to convenient intermediates for PS-5, PS-6, asparenomycin, and thienamycin are described.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo00289a035