Synthesis of Novel2-{[6-(3,5-Dimethyl-1H-pyrazol-1-yl)pyridazin-3-yl]thio}acetohydrazide Derivatives and Their Biological Properties

Pyrazolylpyridazine is an interesting non-fused biheterocyclic system, which derivatives have a wide spectrum of biological activity. In this study, a targeted synthesis of a number of new potentially biologically active derivatives based on the corresponding 2-{[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyri...

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Bibliographic Details
Published inRussian journal of general chemistry Vol. 92; no. 11; pp. 2492 - 2499
Main Authors Gomktsyan, T. A., Shainova, R. S., Karapetyan, A. V., Ghazaryan, E. A., Harutyunyan, S. V., Vorskanyan, A. S., Yengoyan, A. P., Pivazyan, V. A.
Format Journal Article
LanguageEnglish
Published NEW YORK Springer Nature 01.11.2022
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
1,3,4-thiadiazole(oxadiazole)-2-thione
FUNGICIDAL ACTIVITY
1,2,4-triazole-3-thiol
PYRAZOLE DERIVATIVES
HERBICIDAL ACTIVITY
pyrazolylpyridazin-3-ylthioacetohydrazide
INHIBITORS
plant growth stimulants
arylideneacetohydrazides
E,Z-isomerism
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Summary:Pyrazolylpyridazine is an interesting non-fused biheterocyclic system, which derivatives have a wide spectrum of biological activity. In this study, a targeted synthesis of a number of new potentially biologically active derivatives based on the corresponding 2-{[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazin-3-yl]thio}acetohydrazide was carried out. The synthesized compounds showed a pronounced stimulating effect on plant growth.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363222110354