ANTITUMORAL ALKALOIDS FROM CLAUSEA LANSIUM

Three new carbazole alkaloids, mafaicheenamine A-C (1-3), along with five know compounds (4-8) were isolated from the twitzs of Clausena lansium. All compounds were characterized by the analysis of spectroscopic methods. In addition, the evaluation of antitumoral activity against three human cancer...

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Bibliographic Details
Published inHeterocycles Vol. 81; no. 5; pp. 1261 - 1269
Main Authors Maneerat, Wisanu, Laphookhieo, Surat
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 01.05.2010
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
HIV
BARK
CARBAZOLE ALKALOIDS
CONSTITUENTS
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Summary:Three new carbazole alkaloids, mafaicheenamine A-C (1-3), along with five know compounds (4-8) were isolated from the twitzs of Clausena lansium. All compounds were characterized by the analysis of spectroscopic methods. In addition, the evaluation of antitumoral activity against three human cancer cell lines, KB, MCF-7 and NCI-H187, of compounds 1, 2 and 4-8 were also reported.
ISSN:0385-5414
1881-0942
DOI:10.3987/COM-10-11924