KAI(SO4)(2).12H(2)O as a recyclable Lewis acid catalyst for synthesis of some new oxindoles in aqueous media

Potassium aluminum sulfate (Alum) efficiently catalyses the electrophilic substitution reaction of indole and isatin in aqueous solution at room temperature and under microwave irradiation to afford the new corresponding bis(indol-3-yl)methanes (DIM) and the new corresponding oxindoles.

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Bibliographic Details
Published inJournal of chemical research no. 6; pp. 424 - 426
Main Authors Azizian, J, Mohammadi, AA, Karimi, AR, Mohammadizadeh, MR
Format Journal Article
LanguageEnglish
Published LONDON Sage 01.06.2004
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
indole
CANCER CELLS
ISATINS
microwave irradiation
CONDENSATION
oxindole
INDOLE-3-CARBINOL
3,3'-DIINDOLYLMETHANE DIM
DIINDOLYLMETHANE
isatin
ELECTROPHILIC SUBSTITUTION
alum
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Summary:Potassium aluminum sulfate (Alum) efficiently catalyses the electrophilic substitution reaction of indole and isatin in aqueous solution at room temperature and under microwave irradiation to afford the new corresponding bis(indol-3-yl)methanes (DIM) and the new corresponding oxindoles.
ISSN:1747-5198
2047-6507