An efficient one-pot procedure for preparation of 2,4(1H,3H)-qninazolinediones and 2-thioxoquinazolinone derivatives under microwave irradiation

An efficient one-pot synthesis of 2,4(1H,3H)-quinazolinediones and 2-thioxoquinazolinone derivatives are given by the condensation of isatoic anhydride, primary amine and urea or thiourea in the absence of organic or inorganic reagents under microwave irradiation.

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Bibliographic Details
Published inSynthetic communications Vol. 33; no. 3; pp. 415 - 420
Main Authors Azizian, J, Mohammadi, AA, Karimi, AR
Format Journal Article
LanguageEnglish
Published NEW YORK Marcel Dekker Inc 01.01.2003
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:An efficient one-pot synthesis of 2,4(1H,3H)-quinazolinediones and 2-thioxoquinazolinone derivatives are given by the condensation of isatoic anhydride, primary amine and urea or thiourea in the absence of organic or inorganic reagents under microwave irradiation.
ISSN:0039-7911
DOI:10.1081/SCC-120015771