Synthesis and transformations of 20-isoxazolylsteroids with modified D ring: I. Synthesis of 16 alpha,17 alpha-epoxyderivatives

Synthesis of 16 alpha, 17 alpha -epoxy-20-isoxazolylsteroids was carried out starting with dehydro-pregnenolone acetate. Transformation procedures for preparation therefrom of open-chain compounds were considered. Physico-chemical characteristics of compounds synthesized were investigated.

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Bibliographic Details
Published inRussian journal of organic chemistry Vol. 37; no. 6; pp. 787 - 792
Main Authors Litvinovskaya, RP, Drach, SV, Khripach, VA
Format Journal Article
LanguageEnglish
Published NEW YORK Springer Nature 01.06.2001
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:Synthesis of 16 alpha, 17 alpha -epoxy-20-isoxazolylsteroids was carried out starting with dehydro-pregnenolone acetate. Transformation procedures for preparation therefrom of open-chain compounds were considered. Physico-chemical characteristics of compounds synthesized were investigated.
ISSN:1070-4280
1608-3393
DOI:10.1023/A:1012497111832