Percutaneous coronary intervention vs. medical therapy in patients on dialysis with coronary artery disease in China

• Published in: 中华医学杂志英文版 Vol. 138; no. 3; pp. 301 - 310
• Main Authors: Xie Enmin, Wu Yaxin, Ye Zixiang, He Yong, Zeng Hesong, Luo Jianfang, Chen Mulei, Pang Wenyue, Xu Yanmin, Gao Chuanyu, Guo Xiaogang, Cai Lin, Ji Qingwei, Yang Yining, Wu Di, Yuan Yiqiang, Wan Jing, Ma Yuliang, Zhang Jun, Du Zhimin, Yang Qing, Cheng Jinsong, Ding Chunhua, Ma Xiang, Yin Chunlin, Fan Zeyuan, Tang Qiang, Li Yue, Sun Lihua, Lu Chengzhi, Chi Jufang, Yao Zhuhua, Gao Yanxiang, Yu Changan, Ren Jingyi, Zheng Jingang
• Format: Journal Article
• Language: Chinese
• Published: Department of Cardiology, China-Japan Friendship Hospital, Beijing 100029, China%Department of Cardiology, China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100029, China%Department of Cardiology, Fuwai Central China Cardiovascular Hospital, Zhengzhou, Henan 450003, China%Department of Cardiology, Peking University China-Japan Friendship School of Clinical Medicine, Beijing 100029, China%Department of Cardiology, West China Hospital, Chengdu, Sichuan 610041, China%Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China%Department of Cardiology, Guangdong Provincial People’s Hospital, Guangzhou, Guangdong 510080, China%Department of Cardiology, Beijing Chaoyang Hospital, Beijing 100020, China%Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 117004, China%Department of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 300192, China%Department of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China%Department of Cardiology, The Third People’s Hospital of Chengdu, Chengdu, Sichuan 610014, China%Department of Cardiology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi 530021, China%Department of Cardiology, People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang 830001, China%Department of Cardiology, Emergency General Hospital, Beijing 100028, China%Department of Cardiology, Henan Provincial Chest Hospital, Zhengzhou, Henan 450003, China%Department of Cardiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China%Department of Cardiology, Peking University People’s Hospital, Beijing 100044, China%Department of Cardiology, Cangzhou Central Hospital of Tianjin Medical University, Cangzhou, Hebei 061001, China%Department of Cardiology, Dongguan Tungwah Hospital, Dongguan, Guangdong 523015, China%Department of Cardiology, Tianjin Medical University General Hospital, Tianjin 300052, China%Department of Cardiology, Ningbo First Hospital, Ningbo, Zhejiang 315010, China%Department of Cardiology, Aerospace Center Hospital, Beijing100049, China%Department of Cardiology, The First Affiliated Hospital of Xinjiang Medical University, Xinjiang 830011, China%Department of Cardiology, Xuanwu Hospital, Beijing 100053, China%Department of Cardiology, Civil Aviation General Hospital, Beijing 100123, China%Department of Cardiology, Peking University Shougang Hospital, Beijing 100144, China%Department of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150001, China%Department of Cardiology, Fifth Affiliated Hospital of Xinjiang Medical University, Xinjiang 830000, China%Department of Cardiology, First Central Hospital of Tianjin, Tianjin 300190, China%Department of Cardiology, Shaoxing People’s Hospital, Shaoxing, Zhejiang 312099, China%Department of Cardiology, Tianjin Union Medicine Center, Tianjin 300121, China 2025
• Subjects: End-stage renal disease; Prognosis; Dialysis; Percutaneous coronary intervention; Coronary artery disease
• ISSN: 0366-6999
• DOI: 10.1097/CM9.0000000000003295

Background::The available evidence regarding the benefits of percutaneous coronary intervention (PCI) on patients receiving dialysis with coronary artery disease (CAD) is limited and inconsistent. This study aimed to evaluate the association between PCI and clinical outcomes as compared with medical therapy alone in patients undergoing dialysis with CAD in China.Methods::This multicenter, retrospective study was conducted in 30 tertiary medical centers across 12 provinces in China from January 2015 to June 2021 to include patients on dialysis with CAD. The primary outcome was major adverse cardiovascular events (MACE), defined as a composite of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke. Secondary outcomes included all-cause death, the individual components of MACE, and Bleeding Academic Research Consortium criteria types 2, 3, or 5 bleeding. Multivariable Cox proportional hazard models were used to assess the association between PCI and outcomes. Inverse probability of treatm