Nucleic acids encoding nitrilases

The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.

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Bibliographic Details
Main Authors DeSantis, Grace, Chi, Ellen, Chaplin, Jennifer Ann, Milan, Aileen, Short, Jay, Weiner, David, Madden, Mark, Burk, Mark, Robertson, Dan
Format Patent
LanguageEnglish
Published 18.12.2012
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Summary:The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.