Mitotic kinesin inhibitor

1 2 6 6 3 19 19 4 5 A mitotic kinesin Eg5 inhibitor which comprises a thiadiazoline derivative represented by the general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein Rrepresents a hydrogen atom and the like, Rrepresents a hydrogen atom, -C(═W)R(wherei...

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Bibliographic Details
Main Authors Kato, Kazuhiko, Kitamura, Yushi
Format Patent
LanguageEnglish
Published 27.11.2012
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Summary:1 2 6 6 3 19 19 4 5 A mitotic kinesin Eg5 inhibitor which comprises a thiadiazoline derivative represented by the general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein Rrepresents a hydrogen atom and the like, Rrepresents a hydrogen atom, -C(═W)R(wherein W represents an oxygen atom or a sulfur atom, and Rrepresents substituted or unsubstituted lower alkyl and the like) and the like, Rrepresents -C(═Z)R(wherein Z represents an oxygen atom or a sulfur atom, and Rrepresents substituted or unsubstituted lower alkyl and the like) and the like, Rrepresents substituted or unsubstituted lower alkyl and the like, and Rrepresents substituted or unsubstituted aryl and the like] and the like are provided.