Immunosuppressive polypeptides and nucleic acids

The invention provides immunosuppressive polypeptides and nucleic acids encoding such polypeptides. In one aspect, the invention provides mutant CTLA-4 polypeptides and nucleic acids encoding mutant CTLA-4 polypeptides. Compositions and methods for utilizing such polypeptides and nucleic acids are a...

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Bibliographic Details
Main Authors Karrer, Erik E, Paidhungat, Madan M, Bass, Steven H, Neighbors, Margaret, Punnonen, Juha, Chapin, Steven J
Format Patent
LanguageEnglish
Published 27.11.2012
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Summary:The invention provides immunosuppressive polypeptides and nucleic acids encoding such polypeptides. In one aspect, the invention provides mutant CTLA-4 polypeptides and nucleic acids encoding mutant CTLA-4 polypeptides. Compositions and methods for utilizing such polypeptides and nucleic acids are also provided.