4-hydroxythiobenzamide derivatives of drugs

Derivatives of drugs are provided, said derivatives comprising the H2S-releasing moiety 4-hydroxythiobenzamide that is either covalently linked to the drug or forms a salt with the drug. The compounds of the present invention exhibit enhanced activity or reduced side effects or both.

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Bibliographic Details
Main Authors Wallace, John, Cirino, Giuseppe, Santagada, Vincenzo, Caliendo, Giuseppe
Format Patent
LanguageEnglish
Published 20.11.2012
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Summary:Derivatives of drugs are provided, said derivatives comprising the H2S-releasing moiety 4-hydroxythiobenzamide that is either covalently linked to the drug or forms a salt with the drug. The compounds of the present invention exhibit enhanced activity or reduced side effects or both.