Oral care compositions containing combinations of anti-bacterial and host-response modulating agents

The present invention encompasses topical oral care compositions comprising the combination of an anti-bacterial agent with an anti-inflammatory agent in an orally acceptable carrier for effective treatment and prevention of bacteria-mediated diseases and conditions in the oral cavity and for modula...

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Bibliographic Details
Main Authors Doyle, Matthew Joseph, Laughlin, Leo Timothy, Underiner, Todd Laurence, Ho, Begonia Y, Grayling, Rowan Andrew
Format Patent
LanguageEnglish
Published 09.10.2012
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Summary:The present invention encompasses topical oral care compositions comprising the combination of an anti-bacterial agent with an anti-inflammatory agent in an orally acceptable carrier for effective treatment and prevention of bacteria-mediated diseases and conditions in the oral cavity and for modulating host reaction to bacterial pathogens present in the oral cavity and to the toxins, endotoxins, inflammatory cytokines and mediators released by or prompted by these pathogens. The present invention also encompasses methods of use of these compositions comprising topical application to the oral cavity. The benefits of the present compositions and methods extend beyond treating and preventing oral bacterial infections in the oral cavity to promoting whole body or systemic health.