Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders

Compounds of formula (I): or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful for the treatment of metabolic disorders including obesity.

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Main Authors Bloxham, Jason, Bradley, Stuart Edward, Dupree, Tom Banksia, Fry, Peter Timothy, Hanrahan, Patrick Eric, Krulle, Thomas Martin, Procter, Martin James, Sambrook-Smith, Colin Peter, Schofield, Karen Lesley, Smyth, Donald, Stewart, Alan John
Format Patent
LanguageEnglish
Published 02.10.2012
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Summary:Compounds of formula (I): or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful for the treatment of metabolic disorders including obesity.