Solid pharmaceutical dispersions with enhanced bioavailability

Spray dried solid dispersions comprising a sparingly soluble drug and hydroxypropylmethylcellulose acetate succinate (HPMCAS) provide increased aqueous solubility and/or biavailability in a use environment.

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Bibliographic Details
Main Authors Curatolo, William J, Herbig, Scott M, Nightingale, James A. S
Format Patent
LanguageEnglish
Published 11.09.2012
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Summary:Spray dried solid dispersions comprising a sparingly soluble drug and hydroxypropylmethylcellulose acetate succinate (HPMCAS) provide increased aqueous solubility and/or biavailability in a use environment.