Pyrimidine hydrazide compounds as PGDS inhibitors

1234 1 This invention is directed to a compound of formula (I): wherein R, R, R, Rand Lare as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma an...

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Main Authors Aldous, Suzanne C, Fennie, Michael W, Jiang, John Z, John, Stanly, Mu, Lan, Pedgrift, Brian, Pribish, James R, Rauckman, Barbara S, Sabol, Jeffrey S, Stoklosa, Grzegorz T, Thurairatnam, Sukanthini, Vandeusen, Christopher Loren
Format Patent
LanguageEnglish
Published 04.09.2012
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Summary:1234 1 This invention is directed to a compound of formula (I): wherein R, R, R, Rand Lare as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).