Dispersible macromolecule compositions and methods for their preparation and use

A process for preparing ultrafine powders of biological macromolecules comprises atomizing liquid solutions of the macromolecules, drying the droplets formed in the atomization step, and collecting the particles which result from drying. By properly controlling each of the atomization, drying, and c...

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Bibliographic Details
Main Authors Platz, Robert M, Brewer, Thomas K, Boardman, Terence D
Format Patent
LanguageEnglish
Published 08.05.2012
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Summary:A process for preparing ultrafine powders of biological macromolecules comprises atomizing liquid solutions of the macromolecules, drying the droplets formed in the atomization step, and collecting the particles which result from drying. By properly controlling each of the atomization, drying, and collection steps, ultrafine dry powder compositions having characteristics particularly suitable for pulmonary delivery for therapeutic and other purposes may be prepared.