N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes

This invention relates to compounds that are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. The compounds are of the general formula (I) wherein A and B are further define...

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Main Authors Lau, Jesper, Vedsø, Per, Kodra, János Tibor, Murray, Anthony, Jeppesen, Lone, Ankersen, Michael, Subramanian, Govindan, Mjalli, Adnan M. M, Andrews, Robert Carl, Polisetti, Dharma Rao, Christen, Daniel Peter
Format Patent
LanguageEnglish
Published 03.04.2012
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Summary:This invention relates to compounds that are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. The compounds are of the general formula (I) wherein A and B are further defined in the application.