Nasal calcitonin formulations containing chlorobutanol

An aqueous solution of calcitonin suitable for intranasal administration comprised of calcitonin, chlorobutanol at a concentration of less than 0.4% weight/weight, and water and having a pH of less than 4 with the proviso that benzalkonium chloride is not present in the solution. The aqueous solutio...

Full description

Saved in:
Bibliographic Details
Main Authors Quay, Steven C, de Meireles, Jorge C, Deshpande, Arati, Go, Zenaida O, Sileno, Anthony P
Format Patent
LanguageEnglish
Published 20.03.2012
Online AccessGet full text

Cover

More Information
Summary:An aqueous solution of calcitonin suitable for intranasal administration comprised of calcitonin, chlorobutanol at a concentration of less than 0.4% weight/weight, and water and having a pH of less than 4 with the proviso that benzalkonium chloride is not present in the solution. The aqueous solution of calcitonin can be used to treat osteoporosis, Paget's bone disease and hypercalcemia.