Anti-IL-17 antibodies

Anti-IL-17 antibodies are identified that are characterized as having a high affinity and slow off rate for human IL-17. The antibodies of the invention may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of th...

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Bibliographic Details
Main Authors Allan, Barrett, Chow, Chi-Kin, Liu, Ling, Lu, Jirong, Tetreault, Jonathan Wendell, Tang, Ying
Format Patent
LanguageEnglish
Published 07.02.2012
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Summary:Anti-IL-17 antibodies are identified that are characterized as having a high affinity and slow off rate for human IL-17. The antibodies of the invention may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful in particular for treating autoimmune, inflammatory, cell proliferative and developmental disorders.