Renin inhibitors

The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a sub...

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Main Authors Baldwin, John J, Cacatian, Salvacion, Claremon, David A, Dillard, Lawrence W, Flaherty, Patrick T, Ishchenko, Alexey V, Jia, Lanqi, McGeehan, Gerard, Simpson, Robert D, Singh, Suresh B, Tice, Colin M, Xu, Zhenrong, Yuan, Jing, Zhao, Wei, Zhuang, Linghang
Format Patent
LanguageEnglish
Published 31.01.2012
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Summary:The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.