Acellular dermal matrix and method of use thereof for grafting

A method for processing and preserving an acellular collagen-based tissue matrix for transplantation is disclosed. The method includes the steps of processing biological tissues with a stabilizing solution to reduce procurement damage, treatment with a processing solution to remove cells, treatment...

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Bibliographic Details
Main Authors Livesey, Stephen A, del Campo, Anthony A, Nag, Abhijit, Nichols, Ken B, Griffey, Edward S, Coleman, Christopher
Format Patent
LanguageEnglish
Published 29.11.2011
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Summary:A method for processing and preserving an acellular collagen-based tissue matrix for transplantation is disclosed. The method includes the steps of processing biological tissues with a stabilizing solution to reduce procurement damage, treatment with a processing solution to remove cells, treatment with a cryoprotectant solution followed by freezing, drying, storage and rehydration under conditions that preclude functionally significant damage and reconstitution with viable cells.