Phosphorus-containing compounds and uses thereof

• Main Authors: Berstein, David L, Rozamus, Leonard W, Wang, Yihan, Metcalf, III, Chester A
• Format: Patent
• Language: English
• Published: 15.11.2011

2222 25 2 5 6 5525525 25 6 2xThis invention concerns a new family of phosphorus-containing compounds containing a moiety JQA- in which:A is absent or is -O-, -S- or -NR-;Q is absent or (if A is -O-, -S- or -NR-) Q may be -V-, -OV-, -SV-, or -NRV-, where V is an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, such that J is linked to the cyclohexyl ring directly, through A or through VA, OVA, SVA or NRVA; K is O or S; each occurrence of Y is independently -O-, -S-, -NR-, or a bond linking a Rmoiety to P; each occurrence of Rand Ris independently an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, or H; and each occurrence of Ris independently -PK(YR)(YR), -SO(YR) or -C(O)(YR); so long as any R, or Rmoiety linked directly to P is not H; wherein two R, Rand/or Rmoieties may be chemically linked to one another to form a ring; each occurrence of G is independently -O-, -S-, -NR- or (M); each occurrence of M is independently a substituted or unsubstituted methylene moiety, and any M-M′ moiety may be saturated or unsaturated; each occurrence of x is independently an integer from 1-6; and the other variables are as defined herein.