SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors

Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, adva...

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Main Authors Bellott, Emile M, Bu, Dongsheng, Childs, James J, Lambert, Christopher, Nienaber, Hubert A, Shi, Shirley J, Wang, Zhaolin, Workman, Jerome J, Zelenchuk, Alex R
Format Patent
LanguageEnglish
Published 04.10.2011
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Summary:Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.