Non-nucleotide composition for inhibiting platelet aggregation

12 This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprisin...

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Main Authors Plourde, Jr, Robert, Shaver, Sammy R, Douglass, III, James G, Watson, Paul S, Boyer, José L, Tu, Chi, Abreo, Melwyn A, Alfaro-Lopez, Lorenzo J, Feng, Yangbo, Harvey, Daniel F, Khasonova, Tatyana V
Format Patent
LanguageEnglish
Published 17.05.2011
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Summary:12 This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a non-nucleotide compound, preferably a P2Yreceptor antagonist compound, wherein said amount is effective to inhibit platelet aggregation. The compounds useful for this invention include compounds of general Formulae I and III-XII, or salts, hydrates, and solvates thereof. The present invention also provides novel compounds of Formulae I and III-XII.