Nanoparticulate fibrate formulations

The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.

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Bibliographic Details
Main Authors Ryde, Tuula, Gustow, Evan E, Ruddy, Stephen B, Jain, Rajeev, Patel, Rakesh, Wilkins, Michael John
Format Patent
LanguageEnglish
Published 26.04.2011
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Summary:The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.