Fused thiazole derivatives as kinase inhibitors

A series of 5,6-dihydro-1,3-benzothiazol-7(4H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PD kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of...

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Main Authors Alexander, Rikki Peter, Aujla, Pavandeep, Batchelor, Mark James, Brookings, Daniel Christopher, Buckley, George Martin, Crepy, Karen Viviane Lucile, Kulisa, Claire Louise, Turner, James Petrie
Format Patent
LanguageEnglish
Published 15.02.2011
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Summary:A series of 5,6-dihydro-1,3-benzothiazol-7(4H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PD kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.