Probe arrangement

A probe arrangement with a probe for local electrophysiological analysis of cells such as patch-clamp techniques for use with atomic force microscopy, has a probe with a cantilever arm connected to a probe holder. The probe has a probe tip at a probing end of the cantilever arm and a fluid channel i...

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Bibliographic Details
Main Authors Meister, André, Polesel-Maris, Jérôme, Gabi, Michael, Zambelli, Tomaso, Vörös, Janos
Format Patent
LanguageEnglish
Published 11.01.2011
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Summary:A probe arrangement with a probe for local electrophysiological analysis of cells such as patch-clamp techniques for use with atomic force microscopy, has a probe with a cantilever arm connected to a probe holder. The probe has a probe tip at a probing end of the cantilever arm and a fluid channel in the cantilever arm connecting a probe tip aperture with a fluid reservoir via a duct. The fluid channel, the duct and the fluid reservoir are adapted to be filled with a fluid solution enabling ion transport for electrophysiological analysis. A first electrode for electrophysiological analysis is placed in the fluid reservoir and/or in the duct and/or in the fluid channel.