Method for determining the immunogenicity of an antigen

The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines...

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Bibliographic Details
Main Authors Warren, William L, Drake, III, Donald, Moser, Janice, Singh, Inderpal, Song, Haifeng, Mishkin, Eric
Format Patent
LanguageEnglish
Published 31.08.2010
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Summary:The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.