Preparation of metal mesoporphyrin compounds

A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. Th...

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Main Authors Vukovich, Robert A, Levinson, Benjamin, Drummond, George S, Caroselli, Robert, Antczak, Kazimierz G, Boucher, Christopher P, Mortimer, Richard, Levin, Daniel, Cooke, Keith A
Format Patent
LanguageEnglish
Published 17.08.2010
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Summary:A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.