Hsp90 family protein inhibitors

1 78 2 3 54 6The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoyl compound represented by general formula (I): (wherein n represents an integer of 0 to 10; Rrepresents substituted or unsubstituted lower alkoxy, substituted or unsubstituted low...

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Bibliographic Details
Main Authors Nara, Shinji, Nakagawa, Hiroshi, Kanda, Yutaka, Nakashima, Takayuki, Soga, Shiro, Kajita, Jiro, Saito, Jun-ichi, Shiotsu, Yukimasa, Akinaga, Shiro
Format Patent
LanguageEnglish
Published 03.08.2010
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Summary:1 78 2 3 54 6The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoyl compound represented by general formula (I): (wherein n represents an integer of 0 to 10; Rrepresents substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkoxycarbonyl, CONRRor the like; Rrepresents substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group or the like; Rand R, which may be the same or different, each represent a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl or the like; and Rand R, which may be the same or different, each represent a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl or the like) or a prodrug thereof, or a pharmaceutically acceptable salt of said benzoyl compound or said prodrug.