4-Amino-5-oxo-8-phenyl-5H-pyrido(2,3-D) pyrimidine derivatives as tyrosine kinase and raf kinase inhibitors for the treatment of tumours

67891 Compounds of the formula (I), in which R, R, R, R, Het, X and X′ have the meanings indicated in claim , are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours.

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Bibliographic Details
Main Authors Hoelzemann, Guenter, Ackermann, Karl-August, Crassier, Helene, Jonczyk, Alfred, Rautenberg, Wilfried, Tarrason, Gema, Rosell-Vives, Elisabet, Adan, Jaume, Cases, Claudia
Format Patent
LanguageEnglish
Published 29.06.2010
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Summary:67891 Compounds of the formula (I), in which R, R, R, R, Het, X and X′ have the meanings indicated in claim , are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours.