Therapeutic amides

The invention provides compounds of the formula: wherein X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt thereof, intermediates useful for prep...

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Bibliographic Details
Main Authors Horwitz, Jerome P, Corbett, Thomas H, Palomino, Eduardo, Polin, Lisa, Hazeldine, Stuart T
Format Patent
LanguageEnglish
Published 01.06.2010
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Summary:The invention provides compounds of the formula: wherein X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt thereof, intermediates useful for preparing a compound of the above formula, and therapeutic methods comprising administering a compound of the above formula or a salt thereof to a mammal in need thereof.