Sustained delivery of an active agent using an implantable system

The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable...

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Bibliographic Details
Main Authors Peery, John R, Dionne, Keith E, Eckenhoff, James B, Landrau, Felix A, Lautenbach, Scott D, Magruder, Judy A, Wright, Jeremy C
Format Patent
LanguageEnglish
Published 02.02.2010
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Summary:The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.