Azetidine derivatives useful in treating pain, diabetes and disorders of lipid metabolism

12345Disclosed are compounds of the formula: and compounds of the formula: wherein R, R, R, R, R, u and v are as defined herein. Also disclosed are methods of treating pain (e.g., inflammatory pain, chronic pain, and neuropathic pain), methods of treating diabetes, and methods of inhibiting the abso...

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Main Authors McKittrick, Brian A, Smith, Elizabeth M, Bennett, Chad E, Harris, Joel M, Kiselgof, Eugenia Y, Knutson, Chad E, Korakas, Peter, Tulshian, Deen, Kim, Hyunjin
Format Patent
LanguageEnglish
Published 29.12.2009
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Summary:12345Disclosed are compounds of the formula: and compounds of the formula: wherein R, R, R, R, R, u and v are as defined herein. Also disclosed are methods of treating pain (e.g., inflammatory pain, chronic pain, and neuropathic pain), methods of treating diabetes, and methods of inhibiting the absorption of cholesterol using compounds of formula I or IIA.