Stable crystal of 4-oxoquinoline compound

Provision of a stabilized crystal of 6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid (compound A). A crystal of compound A, which shows a particular X-ray powder diffraction pattern of a characteristic diffraction peaks at di...

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Bibliographic Details
Main Authors Satoh, Motohide, Motomura, Takahisa, Matsuda, Takashi, Kondo, Kentaro, Ando, Koji, Matsuda, Koji, Miyake, Shuji, Uehara, Hideto
Format Patent
LanguageEnglish
Published 22.12.2009
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Summary:Provision of a stabilized crystal of 6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid (compound A). A crystal of compound A, which shows a particular X-ray powder diffraction pattern of a characteristic diffraction peaks at diffraction angles 2θ(°) as measured by X-ray powder diffractmetry.