High purity butoconazole nitrate with specified particle size and a process for the preparation thereof

One object of the invention is high purity butoconazole nitrate of the formula (I) (I) containing maximum 0.1 wt % of chemical impurities, wherein at least 95% of the particles of the substance are below 75 μm by diameter, whereas at least 99% of the particles are below 250 μm by diameter, and proce...

Full description

Saved in:
Bibliographic Details
Main Authors Czibula, Laszlo, Dobay, Laszlo, Werkne Papp, Eva, Nagyne Bagdy, Judit, Sebok, Ferenc
Format Patent
LanguageEnglish
Published 01.12.2009
Online AccessGet full text

Cover

More Information
Summary:One object of the invention is high purity butoconazole nitrate of the formula (I) (I) containing maximum 0.1 wt % of chemical impurities, wherein at least 95% of the particles of the substance are below 75 μm by diameter, whereas at least 99% of the particles are below 250 μm by diameter, and process for its preparation. A pharmaceutical composition comprising as active ingredient, high purity butoconazole nitrate of specified particle size in admixture with known auxiliaries is also within the scope of the invention.