Antibodies that bind

M. tuberculosis M. leprae M. tuberculosis. Purified antibodies that bind to ERP protein are disclosed. In one embodiment, a purified antibody, which binds specifically with a polypeptide comprising SEQ ID NO: 39 or SEQ ID NO: 41 is provided. In some embodiments the polypeptide has a theoretical mole...

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Bibliographic Details
Main Authors Gicquel, Brigitte, Lim, Eng Mong, Portnoi, Denis, Berthet, Francois-Xavier, Timm, Juliano
Format Patent
LanguageEnglish
Published 13.10.2009
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Summary:M. tuberculosis M. leprae M. tuberculosis. Purified antibodies that bind to ERP protein are disclosed. In one embodiment, a purified antibody, which binds specifically with a polypeptide comprising SEQ ID NO: 39 or SEQ ID NO: 41 is provided. In some embodiments the polypeptide has a theoretical molecular weight of about 28 kDa. In other embodiments the polypeptide has an observed molecular weight of about 36 kDa, as determined by denaturing polyacrylamide gel electrophoresis (SDS-PAGE). The purified antibody may be a monoclonal or a polyclonal antibody. Further embodiments provide antibodies that does not bind specifically with P28 protein. The antibodies of the invention have many uses including the identification of