Caspase inhibitors containing isoxazoline ring

The present invention relates to an isoxazoline derivative as an inhibitor against various caspases, a process for preparing the same, and a therapeutic composition for preventing inflammation and apoptosis comprising the same.

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Bibliographic Details
Main Authors Chang, Hye-Kyung, Oh, Yeong-Soo, Park, Cheol-Won, Jang, Yong-Jin, Park, Tae-Kyo, Kim, Sung-Sub, Kim, Min-Jung, Park, Mi-Jeong, Park, Jung-Gyu, Park, Hee-Dong, Min, Kyeong-Sik, Lee, Tae-Soo, Lee, Sang-Kyun, Kim, Soo-Hyeon, Jeong, Hee-Kyung, Lee, Sun-Hwa, Kim, Hwa-Dong, Kim, Ae-Ri, Park, Ki-Sook, Shin, Hyun-Ik, Choi, Hyeong-Wook, Lee, Kyu-Woong, Lee, Jae-Hoon, Heo, Tae-Ho, Kim, Ho-Jun, Kwon, Tae-Sik, Seong, Jeong Hui
Format Patent
LanguageEnglish
Published 07.07.2009
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Summary:The present invention relates to an isoxazoline derivative as an inhibitor against various caspases, a process for preparing the same, and a therapeutic composition for preventing inflammation and apoptosis comprising the same.