Active antiangiogenic therapy

Application of oligonucleotide and polypeptide sequences of molecules of the family of the vascular permeability factor (VPF), their receptors, and co-receptors, as well as their modifications, in the active immunotherapy of pathologic entities in which course is associated to the increase of angiog...

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Main Authors Romero, Mónica Bequet, Acevedo Castro, Boris Ernesto, Gavilondo Cowley, Jorge Victor, Fernández Molina, Luis Enrique, Ocejo, Omar Lopez, Silva Rodriguez, Ricardo de la Caridad, Lasa, Alexis Musachio, Rodriguez, Ernesto Galban, Vázquez Blomquist, Dania Marcia
Format Patent
LanguageEnglish
Published 07.07.2009
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Abstract Application of oligonucleotide and polypeptide sequences of molecules of the family of the vascular permeability factor (VPF), their receptors, and co-receptors, as well as their modifications, in the active immunotherapy of pathologic entities in which course is associated to the increase of angiogenesis.These procedures can be employed in the single or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, diabetic and newborn retinopathies, organ transplant rejection, macular degeneration, neovascular glaucoma, hemangioma, and angiofibroma, among others.
AbstractList Application of oligonucleotide and polypeptide sequences of molecules of the family of the vascular permeability factor (VPF), their receptors, and co-receptors, as well as their modifications, in the active immunotherapy of pathologic entities in which course is associated to the increase of angiogenesis.These procedures can be employed in the single or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, diabetic and newborn retinopathies, organ transplant rejection, macular degeneration, neovascular glaucoma, hemangioma, and angiofibroma, among others.
Author Vázquez Blomquist, Dania Marcia
Lasa, Alexis Musachio
Ocejo, Omar Lopez
Romero, Mónica Bequet
Gavilondo Cowley, Jorge Victor
Silva Rodriguez, Ricardo de la Caridad
Acevedo Castro, Boris Ernesto
Fernández Molina, Luis Enrique
Rodriguez, Ernesto Galban
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References Prewett, Marie, et al., "Antivascular Endothelial Growth Factor Receptor (Fetal Liver Kinase 1) Monoclonal Antibody Inhibits Tumor Angiogenesis and Growth of Several Mouse and Human Tumors", Cancer Research 1999, 59:5209-5218.
Rodriguez et al. (6149921) 20001100
Leggatt et al, J Immunology 161: 4728-4735, 1998.
Kobrin et al, J Immunology 146: 2017-2020, 1991.
Lu et al, J Biol Chemistry 275(19): 14321-14330, May 2000.
Stacker et al, J Biol Chemistry 274(49): 34884-92, Dec. 1999.
Siemeister et al, J Biol Chemistry 273(18): 11115-11120, 1998.
Kendall et al. (5712380) 19980100
Stryer et al, in Biochemistry, Third edition, W H Freeman Company, New York, pp. 31-33, 1998.
Davidoff, Andrew M., et al., "Bone Marrow-derived Cells Contribute to Tumor Neovasculature and, When Modified to Express an Angiogenesis Inhibitor, Can Restrict Tumor Growth in Mice", Clinical Cancer Research 2001, 7:2870-2879.
(WO 99/45018) 19990900
Ngo et al., The Protein Folding Problem and Tertiary Structure Prediction, pp. 492-495, 1994.
Wei, Yu-quan, et al., "Immunogene therapy of tumors with vaccine based on Xenopus homologous vascular endothelial growth factor as a model antigen", PNAS 2001, 98(20):11545-11550.
(WO 00/53219) 20000900
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