Active antiangiogenic therapy

Application of oligonucleotide and polypeptide sequences of molecules of the family of the vascular permeability factor (VPF), their receptors, and co-receptors, as well as their modifications, in the active immunotherapy of pathologic entities in which course is associated to the increase of angiog...

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Main Authors Romero, Mónica Bequet, Acevedo Castro, Boris Ernesto, Gavilondo Cowley, Jorge Victor, Fernández Molina, Luis Enrique, Ocejo, Omar Lopez, Silva Rodriguez, Ricardo de la Caridad, Lasa, Alexis Musachio, Rodriguez, Ernesto Galban, Vázquez Blomquist, Dania Marcia
Format Patent
LanguageEnglish
Published 07.07.2009
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Summary:Application of oligonucleotide and polypeptide sequences of molecules of the family of the vascular permeability factor (VPF), their receptors, and co-receptors, as well as their modifications, in the active immunotherapy of pathologic entities in which course is associated to the increase of angiogenesis.These procedures can be employed in the single or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, diabetic and newborn retinopathies, organ transplant rejection, macular degeneration, neovascular glaucoma, hemangioma, and angiofibroma, among others.