Bis-aryl thiazole derivatives

Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by an uncoupling protein. In particular, the compounds of the invention modulate the expression and/or activity of UCP3. The subject compositions are particularly usefu...

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Bibliographic Details
Main Authors Amaral, M. Catherine, Chen, Jin-Long, Jaen, Juan C, Johnston, David N, Rafferty, Paul
Format Patent
LanguageEnglish
Published 15.04.2008
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Summary:Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by an uncoupling protein. In particular, the compounds of the invention modulate the expression and/or activity of UCP3. The subject compositions are particularly useful in the treatment of obesity and type II diabetes, and associated diseases