Substituted acylhydroxamic acids and method of reducing TNFαlevels

Imido and amido substituted acylhydroxamidic acids which reduce the levels of TNFα and inhibit phosphodiesterase in a mammal. A typical embodiment is (3-(1,3-dioxoisoindolin-2-yl)-3-(3-ethoxy-4-methoxyphenyl)propandylamino)propanoate.

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Bibliographic Details
Main Authors Man, Hon-Wah, Muller, George W, Huang, Shaei Y
Format Patent
LanguageEnglish
Published 18.03.2008
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Summary:Imido and amido substituted acylhydroxamidic acids which reduce the levels of TNFα and inhibit phosphodiesterase in a mammal. A typical embodiment is (3-(1,3-dioxoisoindolin-2-yl)-3-(3-ethoxy-4-methoxyphenyl)propandylamino)propanoate.