Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy

222221 1 2 12 The present invention relates to compounds being esters of 5-aminolevulinic acids or pharmaceutically acceptable salts thereof, including compounds of formula (I) RN-CHCOCH-CHCO-OR(wherein Rmay represent alkyl optionally substituted by hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, amino...

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Main Authors Gierskcky, Karl E, Moan, Johan, Peng, Qian, Steen, Harald, Warloe, Trond, Bjorseth, Alf, Klaveness, Jo, Nilsen, Nils, Braenden, Jon Erik, Godal, Aslak
Format Patent
LanguageEnglish
Published 30.10.2007
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Summary:222221 1 2 12 The present invention relates to compounds being esters of 5-aminolevulinic acids or pharmaceutically acceptable salts thereof, including compounds of formula (I) RN-CHCOCH-CHCO-OR(wherein Rmay represent alkyl optionally substituted by hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, amino, aryl, oxo or fluoro groups and optionally interrupted by oxygen, nitrogen, sulphur or phosphorus atoms; and Rrepresents a hydrogen atom or a group R, and both Rgroups may be the identical or different), and their use in diagnosis and photochemotherapy of disorders or abnormalities of external or internal surfaces of the body, and products and kits for performing the invention.