Inhibitors of cyclin dependent kinases as anti-cancer agent

The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders such as cancer, leukaemia, psoriasis...

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Bibliographic Details
Main Authors Fischer, Peter Martin, Wang, Shudong, Wood, Gavin
Format Patent
LanguageEnglish
Published 28.08.2007
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Summary:The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders such as cancer, leukaemia, psoriasis and the like.