Substituted-cycloalkyl and oxygenated-cycloalkyl glucokinase activators

2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.

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Bibliographic Details
Main Authors Corbett, Wendy Lea, Grimsby, Joseph Samuel, Haynes, Nancy-Ellen, Kester, Robert Francis, Mahaney, Paige Erin, Racha, Jagdish Kumar, Sarabu, Ramakanth, Wang, Ka
Format Patent
LanguageEnglish
Published 21.08.2007
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Summary:2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.