Sulfonyl-Derivatives as novel inhibitors of histone deacetylase

1234 This invention comprises the novel compounds of formula (I) wherein n, m, t, R, R, R, R, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine

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Main Authors Van Emelen, Kristof, Arts, Janine, Backx, Leo Jacobus Jozef, De Winter, Hans Louis Jos, Van Brandt, Sven Franciscus Anna, Verdonck, Marc Gustaaf Celine, Meerpoel, Lieven, Pilatte, Isabelle Noëlle Constance, Poncelet, Virginie Sophie, Dyatkin, Alexey Borisovich, Van heusden, Jimmy Arnold Viviane
Format Patent
LanguageEnglish
Published 17.04.2007
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Summary:1234 This invention comprises the novel compounds of formula (I) wherein n, m, t, R, R, R, R, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine