Multiwell plate assembly for use in high throughput assays

A device for characterizing the biological properties of cells can include a plurality of dual-compartment assay chambers wherein the compartments of each chamber are separated by a cell layer across which ions can flow. The biological properties of the cell layer in the presence or absence of exper...

Full description

Saved in:
Bibliographic Details
Main Authors Negulescu, Paul A, Harootunian, Alec T, Salzmann, Philip E, Flores, Javier H, Sinclair, James E, Vuong, Minh, Singh, Ashvani K, VanGoor, Fred F
Format Patent
LanguageEnglish
Published 30.01.2007
Online AccessGet full text

Cover

More Information
Summary:A device for characterizing the biological properties of cells can include a plurality of dual-compartment assay chambers wherein the compartments of each chamber are separated by a cell layer across which ions can flow. The biological properties of the cell layer in the presence or absence of experimental compounds can be determined by measuring an electrical gradient across the layer. A individual dual-compartment chamber of this type may be referred to as an "Ussing chamber."